For Your Beloveds
Our bodies develop form embryonic stem cells (ESCs)...
When we are young, stem cells are rich in our body which means we can grow quickly and have very soft and regenerative skin. However, as we get older and are thus exposed to many kinds of stress factors, the stem cells rapidly lose vitality and become extinct, which results in losing our physical activity and showing the rough wrinkled skin due to limited supply of new epithelial cells. Thus, to help with health maintenance and to overcome incurable diseases, it is possible to restore injured cells and tissues by transplanting stem cells extracted from adipose tissue, umbilical cord, amniotic membrane or other tissues in which lots of stem cells remain.
Designed Cells’ stem cells for the treatment of central nervous system (CNS) diseases are induced neural stem cells (iNSCs) obtained through ethical procedures (IRB). The cells are from safe autologous adipose-derived stem cells (ADSCs) or tissue-compatible amniotic membrane stem cells (AMSCs), and especially provide excellent therapeutic efficacies by expressing target-specific functional genes (Core-technology 1). Another our advanced technology is to obtain high-concentrations (50~100 folds) of stem cell exosomes from the functional gene-encoding stem cells (Core-technology 2).
Item | Adult stem cells (ASCs) | Embryonic stem cells (ESCs) |
Induced pluripotent stem cells (iPSCs) |
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UCBSCs/BMSCs /ADSCs |
iNSC encoding functional genes |
Stem cell exosomes (contents: 50~100 folds) |
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Tumor formation | None | None | None | Possible | Possible |
Effectiveness (CNS diseases) |
Limited | Best(whole cycle of disease) | Excellent(early-middle terms of disease) | Ordinary | Ordinary |
Brain penetration | Sufficient (ICV)/ Limited (IV) |
Sufficient (ICV)/ Limited (IV) |
Sufficient (IV/nasal) | Sufficient (ICV)/ Limited (IV) |
Sufficient (ICV)/ Limited (IV) |
Compatibility & survival | Ordinary | Excellent | Excellent(neuroregeneration) | △ | △ |
Adverse effects | Excellent (autologous)/Ordinary (allogeneic) | Excellent (autologous) | Best | bad | bad |
Collecting times | Repeated | Repeated | Once(immortalized) | Repeated | Once |